Boost nerve growth factor (NGF)*
*Results may vary. Various preclinical & clinical studies using Lion's Mane Mushroom suggest it may enhance NGF synthesis. In addition, studies suggest it may promote healthy cognition, memory & overall nerve/brain health.
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Notable Select™ Lion's Mane is a high potency 20:1 extract derived from the fruiting bodies of organic Lion's Mane mushrooms. Our industry-leading extraction technology unlocks the full power of this mushroom in enhancing memory & overall brain health.
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SUPPLEMENT FACTS
HOW TO USE
Take 1 capsule per day with food or as directed by your healthcare professional.
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
Why
Lion's Mane?
Cognition, Memory, & Nerve Health
Lion’s Mane is packed with bioactive compounds like erinacines, which increase the synthesis of nerve growth factor (NGF) expression. NGF stimulates neurite outgrowth, which is important as it enhances the brain's ability to repair, adapt, and form new connections. NGF promotes axonal regeneration & myelination. In addition to supporting brain health, NGF promotes healthy peripheral nerve function outside of the brain as well.
Mood & Stress
Lion’s Mane promotes healthy mood & stress levels by enhancing brain-derived neurotrophic factor (BDNF) expression & neurosteroid levels in the brain. Lion’s Mane also helps balance neuroinflammation by downregulating IL-1β, IL-6, and TNF-alpha, & iNOS.
Gut & Microbiome Health
Lion's Mane is a rich source of prebiotic fibers called beta-glucans. These fibers promote the growth of "good bacteria" in the gut microbiome while reducing bad bacteria. As a result, this increases butyrate production, which strengthens the gut barrier, balances gastrointestinal inflammation, energizes colon cells, & improves gut motility. Outside of the gut, butyrate is also crucial to optimal metabolic & brain health. In addition to supporting the microbiome & butyrate production, Lion's Mane can downregulate oxidative & inflammatory markers while upregulating gastroprotective markers such as heat shock proteins (e.g. HSP70).
Skin & Immune Health
Studies suggest Lion's Mane can promote a youthful appearance & slow skin aging. Specifically, it contains bioactives that inhibit MMP-1 and thus decrease collagen breakdown as you age. Lion's Mane has also been shown to expedite wound healing & reduce skin irritation. On top of that, Lion's Mane has major immunomodulatory properties and can help balance the immune system by boosting levels of protective immune cells & balancing harmful inflammation.
High Potency*
2x+
More Potent than Leading Brands*
Notable uses a high potency Lion's Mane extract that is over 2x more concentrated than competitors
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
"Notable has also garnered strong endorsements from influential health authorities on Twitter" - Business Insider
"Notable strives to represent a new era of excellence in the supplement industry" - Yahoo Finance
“Notable has emerged as a solution to the limitations of conventional treatments” - ABC
"Notable is a game-changer" - MarketWatch
"Top-notch formulation, manufacturing, and quality control processes" - Bloomberg
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FAQ
What is Lion's Mane?
Lion’s Mane is a mushroom that has been consumed throughout the world for thousands of years. Lion’s Mane has grown in popularity during the past few years due to its many potential cognitive & gut health benefits.
What are the benefits of Lion’s Mane? Is it scientifically backed?
Many recent human studies have shown that Lion’s Mane can improve aspects of cognition in certain populations. Many scientists believe that these benefits result in part from a molecule called Erinacine A, which can enhance the production of Nerve Growth Factor (NGF). In simple terms, NGF is like miracle grow for neurons & neural networks. Additional studies suggest Lion’s Mane may benefit the gut microbiome, immune system, & even skin aesthetics.
Why should I choose Notable Select™ Lion’s Mane over other Lion’s Mane products?
Notable Select™ Lion’s Mane stands out for its high potency & exceptional purity. We use a 20:1 extract, which means we use 20g of raw organic Lion’s Mane fruiting bodies for every 1g of extract produced. Many brands on the market use weaker extracts (e.g. 8:1, 2:1, 1:1), which are usually less concentrated with the mushroom’s key biologically active constituents.
How soon can I expect results?
Results may vary, but many begin to see improvements to cognition within 2 to 4 weeks. These benefits build with consistent use.
When is the best time to take Lion's Mane?
Lion’s Mane can be taken anytime, with or without food.
Can I take Lion’s Mane if I'm already taking other supplements or medications?
We advise customers to talk to their doctor before starting any new dietary supplement, especially if they are taking prescription drugs.